Medium Optimization by Response Surface Methodology for Improved Cholesterol Oxidase Production by a Newly Isolated Streptomyces rochei NAM-19 Strain

Table 3

Regression analysis of PBD with model coefficients and significance of the regression coefficient for CO activity.

Term	Effect	Coefficient	SE coefficient	T-value	value
Constant		9.700	1.280	7.570	0.000
X1	3.616	1.808	0.107	16.84	0.000
X2	−2.191	−1.096	0.107	−10.20	0.000
X3	0.542	0.271	0.107	2.500	0.040
X4	0.783	0.391	0.123	3.19	0.015