Development of Autophagy Signature-Based Prognostic Nomogram for Refined Glioma Survival Prognostication

Figure 7

The functional enrichment analysis and immune statue estimation. (a) Heat map of the entire GEO microarray genes bifurcated by the signature risk score median into high- and low-risk groups. (b) Volcano plot of the differentially expressed genes between the high- and low-risk groups, the cutoff value was calculated as 0.85. (c) Bubble plot for the top 9 results of the GO analysis of the DEGs between the two risk groups. (d) Enrichment map auto-annotated for the representation of the GSEA results with , NOM value < 0.05, and FDR value < 0.25. (e) Boxplot for the estimation of the immune and stromal status of the two risk groups in the GEO cohort. (f) Circos plot for representation of the correlations among risk score and immune checkpoint genes.

(a)

(b)

(c)

(d)

(e)

(f)