Employment of Alginate Floating In Situ Gel for Controlled Delivery of Celecoxib: Solubilization and Formulation Studies

Table 5

Anti-inflammatory effect of F3, reference, and control in carrageenan-induced paw edema in rats.

Group	Treatment	Initial paw volume	Paw volume (mL)				Edema inhibition at 8 hs (%)
			1 hour	3 hours	5 hours	8 hours
I	Control						—
II	Reference						75.83
III	F3						92.64

Values are represented as , in each group, two-way ANOVA followed by Bonferroni’s multiple comparisons, .