Research Article

[Retracted] LINC00511 Promotes Osteosarcoma Tumorigenesis and Invasiveness through the miR-185-3p/E2F1 Axis

Figure 5

miR-185-3p/E2F1 axis was the downstream targets of LINC00511 in osteosarcoma cells. (a) The analysis of LINC00511 expression after cells transfected with miR-185-3p by qRT-PCR. (b) Relative miR-185-3p expression levels of SW1353 cells and U2OS cells with si-LINC00511 or si-NC. (c, d) Relative E2F1 expression levels of SW1353 cells and U2OS cells with LINC00511 knockdown (c) and miR-185-3p overexpression (d). (e) Dual-luciferase reporter assay in HEK293T cells cotransfected with the wild-type LINC00511 or E2F1 and control miR-NC or miR-185-3p mimics. (f) Luciferase activities of HEK293T cells cotransfected with the LINC00511-mut or E2F1-mut and control miR-NC or miR--185-3p mimics. , .
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