Research Article

Withania frutescens. L Extract: Phytochemical Characterization and Acute and Repeated Dose 28-Day Oral Toxicity Studies in Mice

Table 1

Identification of phytochemical compounds contained in the W. frutescens root extract.

PeakRTPhytochemical compounds identifyArea (%)

115.0873,3,6-tTrimethyl-1,4-heptadien-6-ol (C10H18O)2.54
214.151Tricyclo[2.2.1.0(2,6)]heptane-3-methanol, 2,3-dimethyl-(C10H16O)1.14
313.280Bicyclo[3.1.0]hexan-3-one, 4-methyl-1-(1-methylethyl)-, [1S-(1α,4β,5α)]-(C10H16O)2.35
412.983Bicyclo[2.2.1]heptan-2-ol, 1,7,7-trimethyl-(C10H18O)4.84
512.782Bicyclo[3.1.1]heptan-3-ol, 2,6,6-trimethyl-, (1α,2β,3α,5α)-(C10H18O)0.82
611.5252,6-Octadien-1-ol, 3,7-dimethyl-, (Z)-(C10H18O)2.04
711.0352,6-Octadien-1-ol, 3,7-dimethyl-, (E)-(C10H18O)0.99
810.931Benzene, 1-ethyl-2,3-dimethyl-(C10H14)1.26
910.790Benzene, 1-methyl-3-(1-methylethyl)-(C10H14)1.33
109.698Bicyclo[2.2.1]hept-2-ene, 1,7,7-trimethyl-(C10H16)4.56
119.377Bicyclo[2.2.1]hept-2-ene, 2,7,7-trimethyl-(C10H16)10.19
129.100Bicyclo[3.1.1]heptane, 6,6-dimethyl-2-methylene-, (1S)-(C10H16)28.48
137.855Tricyclo[2.2.1.0(2,6)]heptane, 1,7,7-trimethyl-(C10H16)3.90
145.028Thiophene, 3-phenyl-(C10H8S)0.76
154.952Methanamine,N,N-di(2-trimethylsilyloxyethyl)-(C11H29NO2Si2)34.12
164.852Silanamine, N,1,1,1-tetramethyl-N-(trimethylsilyl)-(C7H21NSi2)0.66
Total99.98