Research Article
A Functional Polymorphism in the Promoter Region of Interleukin-12B Increases the Risk of Colorectal Cancer
Table 3
Stratified analyses of the association between rs17860508 and clinical characteristics of CRC patients.
| | Clinical characteristics | Cases n = 329 | TTAGAG/TTAGAG n (%) | TTAGAG/GC n (%) | GC/GC n (%) | |
| | Differentiation | | | | | | | Good + moderate | 260 | 60 (23.1) | 129 (49.6) | 71 (27.3) | | | Poor | 69 | 11 (15.9) | 38 (55.1) | 20 (29.0) | 0.436 | | Clinical stage | | | | | | | I-II | 205 | 50 (24.4) | 101 (49.3) | 54 (26.3) | | | III-IV | 124 | 21 (16.9) | 66 (53.2) | 37 (29.8) | 0.277 | | Lymph node metastasis | | | | | | | Yes | 112 | 20 (17.9) | 58 (51.8) | 34 (30.4) | | | No | 217 | 51 (23.5) | 109 (50.2) | 57 (26.3) | 0.455 | | Tumor location | | | | | | | Left-sided | 227 | 45 (19.8) | 114 (50.2) | 68 (30.0) | | | Right-sided | 102 | 26 (25.5) | 53 (52.0) | 23 (22.5) | 0.289 |
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Abbreviations: CRC, colorectal cancer.
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