Research Article
A Functional Polymorphism in the Promoter Region of Interleukin-12B Increases the Risk of Colorectal Cancer
Table 4
Stratified analyses of the association between rs3212227 and clinical characteristics of CRC patients.
| | Clinical characteristics | Cases n = 329 | AA n (%) | AC n (%) | CC n (%) | |
| | Differentiation | | | | | | | Good + moderate | 260 | 78 (30.0) | 129 (49.6) | 53 (20.4) | | | Poor | 69 | 18 (26.1) | 31 (44.9) | 20 (29.0) | 0.309 | | Clinical stage | | | | | | | I-II | 205 | 62 (30.2) | 104 (50.7) | 39 (19.0) | | | III-IV | 124 | 34 (27.4) | 56 (45.2) | 34 (27.4) | 0.206 | | Lymph node metastasis | | | | | | | Yes | 112 | 29 (25.9) | 52 (46.4) | 31 (27.7) | | | No | 217 | 67 (30.9) | 108 (49.8) | 42 (19.4) | 0.212 | | Tumor location | | | | | | | Left-sided | 227 | 69 (30.4) | 109 (48.0) | 49 (21.6) | | | Right-sided | 102 | 27 (26.5) | 51 (50.0) | 24 (23.5) | 0.760 |
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Abbreviations: CRC, colorectal cancer.
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