OSCC Exosomes Regulate miR-210-3p Targeting EFNA3 to Promote Oral Cancer Angiogenesis through the PI3K/AKT Pathway

Figure 4

EphrinA3 could influence the migration and proliferation of HUVECs. (a) Western blot showed that EphrinA3 was downregulated by si-EphrinA3 compared to NC. . (b–d) Migration and CCK-8 assays showed that migration and proliferation were promoted in HUVECs when ephrinA3 was reduced by si-EphrinA3. (e) Fluorescence microscopy suggested that the transfection of the vector and lentivirus was successful, and its efficiency was about 90%. Scale bar, 50 μm. (f) EphrinA3 was upregulated by lentivirus. . (g–i) Migration and proliferation of HUVECs were restrained after upregulating the ephrinA3. , . Scale bar, 50 μm.

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