Identification of Four Pathological Stage-Relevant Genes in Association with Progression and Prognosis in Clear Cell Renal Cell Carcinoma by Integrated Bioinformatics Analysis

<div>Validation of RNA and protein expression levels for hub genes. (a) Experimental validation of UBE2C, BUB1B, RRM2, and TPX2 in 8 paired clinical ccRCC samples. 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22C152 22 124 173 124 313S148 602 238 602Z"></path></g><g transform="matrix(.013,0,0,-0.013,73.667,0)"><path d="M384 0V27C293 34 287 42 287 114V635C232 613 172 594 109 583V559L157 557C201 555 205 550 205 499V114C205 42 199 34 109 27V0H384Z"></path></g></svg>.</span> (b) UBE2C, RRM2, and TPX2 protein expression levels in ccRCC as compared to those in normal kidney tissues by IHC staining. Scale bars represent 100 <i>μ</i>m. Black and red square boxes represent typical normal kidney and ccRCC tissues, respectively.</div>

BioMed Research International

fig5

Figure 5

Figure 5: Identification of Four Pathological Stage-Relevant Genes in Association with Progression and Prognosis in Clear Cell Renal Cell Carcinoma by Integrated Bioinformatics Analysis 

Figure 5 | Identification of Four Pathological Stage-Relevant Genes in Association with Progression and Prognosis in Clear Cell Renal Cell Carcinoma by Integrated Bioinformatics Analysis 