Identification of Four Pathological Stage-Relevant Genes in Association with Progression and Prognosis in Clear Cell Renal Cell Carcinoma by Integrated Bioinformatics Analysis

Table 3

Four key hub genes selected from among 500 DEGs and 21 common hub genes from GSE73731 and TCGA-KIRC data.

Gene symbol	Description	Log FC in stage I	Log FC in stage II	Log FC in stage III	Log FC in stage IV
UBE2C	Ubiquitin-conjugating enzyme E2C	2.92	2.60	3.68	3.76
BUB1B	BUB1 mitotic checkpoint serine/threonine kinase B	3.07	2.24	3.26	3.19
RRM2	Ribonucleotide reductase regulatory subunit M2	3.08	2.9	3.74	4.10
TPX2	TPX2 microtubule nucleation factor	2.59	2.51	3.14	3.50