Research Article

Preparation, Optimization, and Evaluation of Epichlorohydrin Cross-Linked Enset (Ensete ventricosum (Welw.) Cheeseman) Starch as Drug Release Sustaining Excipient in Microsphere Formulation

Table 1

Reaction conditions of the eight cross-linked starch formulations for preliminary study.

CLSTheophyllineECH1 M NaOHNaClReactionReactionWeight of dry
Batch(mg)(%,)(%, )(%, )Time (h)To (°C)Enset starch (g)

F-110036.43154100
F-210036.431054100
F-310036.431025100
F-4100166.431025100
F-5100166.43154100
F-6100166.43125100
F-7100166.431054100
F-810036.43125100