Preparation, Optimization, and Evaluation of Epichlorohydrin Cross-Linked Enset (Ensete ventricosum (Welw.) Cheeseman) Starch as Drug Release Sustaining Excipient in Microsphere Formulation

Table 10

Fit summary statistics for DC (%) and drug release rate (h^1/2).

Responses	Source	Std. dev		Adj	Pred	Lack of fit	value	PRESS	Remark
	value
DC (%)	Linear	11.19	0.7904	0.7485	0.6439	0.0316	0.0004	2127.67
	2FI	10.61	0.8303	0.7738	0.5928	0.0354	0.1794	2432.95
	Quadratic	5.89	0.9594	0.9303	0.8188	0.2497	0.0067	1082.65	Suggested
	Cubic	6.69	0.9840	0.9520	0.6943	0.0375	0.2497	2230.82	Aliased
Release rate (h^1/2)	Linear	1.16	0.8357	0.8028	0.6630	0.0891	0.0001	27.79
	2FI	0.78	0.9342	0.9122	0.8633	0.3355	0.0052	11.28	Suggested
	Quadratic	0.86	0.9379	0.8936	0.7051	0.2051	0.8142	24.32
	Cubic	0.67	0.9780	0.9341	0.7284	0.0373	0.2051	26.72	Aliased