Prognostic Value and Clinicopathological Features of MicroRNA-206 in Various Cancers: A Meta-Analysis

Table 3

Association between low miR-206 expression and clinicopathological features.

Clinicopathologic features	No. of studies	No. of patients	Estimate OR (95% CI)	value	Heterogeneity
					(%)	value	Model
Gender (male vs. female)	11	1060	0.88 (0.68-1.14)	0.321	0	0.959	Fixed
Age (old vs. young)	11	1028	1.20 (0.94-1.53)	0.137	0	0.495	Fixed
Tumor diameter (big vs. small)	8	634	1.39 (0.83-2.32)	0.215	57.2	0.022	Random
Tumor stage (III-IV vs. I-II)	10	896	4.20 (2.17-8.13)	≤0.001	75	≤0.001	Random
Tumor differentiation (poor vs. moderate/well)	9	798	1.34 (0.77-2.30)	0.299	65.6	0.003	Random
Lymph node status (yes vs. no)	9	728	3.58 (1.51-8.44)	0.004	81.9	≤0.001	Random
Distant metastasis (yes vs. no)	5	516	3.19 (1.07-9.50)	0.038	67	0.016	Random
Invasion depth ( vs. )	4	538	2.43 (1.70-3.49)	≤0.001	0	0.412	Fixed