Review Article
Prognostic Value and Clinicopathological Features of MicroRNA-206 in Various Cancers: A Meta-Analysis
Table 3
Association between low miR-206 expression and clinicopathological features.
| Clinicopathologic features | No. of studies | No. of patients | Estimate OR (95% CI) | value | Heterogeneity | (%) | value | Model |
| Gender (male vs. female) | 11 | 1060 | 0.88 (0.68-1.14) | 0.321 | 0 | 0.959 | Fixed | Age (old vs. young) | 11 | 1028 | 1.20 (0.94-1.53) | 0.137 | 0 | 0.495 | Fixed | Tumor diameter (big vs. small) | 8 | 634 | 1.39 (0.83-2.32) | 0.215 | 57.2 | 0.022 | Random | Tumor stage (III-IV vs. I-II) | 10 | 896 | 4.20 (2.17-8.13) | ≤0.001 | 75 | ≤0.001 | Random | Tumor differentiation (poor vs. moderate/well) | 9 | 798 | 1.34 (0.77-2.30) | 0.299 | 65.6 | 0.003 | Random | Lymph node status (yes vs. no) | 9 | 728 | 3.58 (1.51-8.44) | 0.004 | 81.9 | ≤0.001 | Random | Distant metastasis (yes vs. no) | 5 | 516 | 3.19 (1.07-9.50) | 0.038 | 67 | 0.016 | Random | Invasion depth ( vs. ) | 4 | 538 | 2.43 (1.70-3.49) | ≤0.001 | 0 | 0.412 | Fixed |
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