Prognostic Values of Transforming Growth Factor-Beta Subtypes in Ovarian Cancer

Table 1

Correlation of TGF-β subtypes with OS and PFS in ovarian cancer patients with different clinical stages of disease.

TGF-β subtypes	Clinical stages	Cases	OS	value	Cases	PFS	value
			HR (95% CI)			HR (95% CI)
TGF-β1	I+II	135	2.62 (1.20-5.73)	0.0012	163	2.40 (1.36-4.23)	0.0018
	III+IV	1220	1.11 (0.94-1.30)	0.21	1081	0.85 (0.74-0.98)	0.023
TGF-β2	I+II	135	0.40 (0.18-0.98)	0.021	163	0.72 (0.41-1.28)	0.26
	III + IV	1220	1.21 (1.04-1.40)	0.011	1081	1.29 (1.12-1.48)	0.0004
TGF-β3	I+II	135	1.83 (0.69-4.88)	0.22	163	1.29 (0.69-2.43)	0.43
	III+IV	1220	1.14 (0.98-1.33)	0.095	1081	1.36 (1.18-1.56)	0.001
TGF-β4	I+II	135	2.96 (1.28-6.85)	0.0079	163	2.18 (1.22-3.87)	0.0068
	III+IV	1220	0.91 (0.78-1.07)	0.26	1081	1.17 (1.02-1.35)	0.029

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