Prognostic Values of Transforming Growth Factor-Beta Subtypes in Ovarian Cancer

Table 3

Correlation of TGF-β subtypes with OS and PFS in ovarian cancer patients with different TP53 mutation statuses.

TGF-β subtypes	TP53 mutation	Cases	OS	value	PFS	value
			HR (95% CI)		HR (95% CI)
TGF-β1	Yes	506	1.16 (0.93-1.46)	0.19	0.79 (0.61-1.03)	0.085
	No	94	1.49 (0.86-2.58)	0.15	0.57 (0.32-1.03)	0.06
TGF-β2	Yes	506	0.86 (0.68-1.20)	0.22	1.25 (1.00-1.56)	0.049
	No	94	1.84 (0.86-3.91)	0.11	1.34 (0.76-2.37)	0.3
TGF-β3	Yes	506	1.38 (1.10-1.73)	0.0055	1.34 (1.07-1.67)	0.0099
	No	94	1.73 (0.99-3.02)	0.05	1.68 (0.95-2.97)	0.073
TGF-β4	Yes	506	1.28 (1.02-1.61)	0.035	1.39 (1.10-1.76)	0.0061
	No	94	1.50 (0.87-2.58)	0.14	1.31 (0.77-2.20)	0.32

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