Relationship between Uric Acid Level and Severity of Acute Primary Cerebral Infarction: A Cross-Sectional Study
Table 2
Baseline characteristics of the participants ().
Characteristic
UA quartiles (μmol/L)
value
Q1 (103-256)
Q2 (262-322)
Q3 (323-384)
Q4 (387-573)
No. of participants
58
59
57
64
Age (years, median, Q1-Q3)
67.50 (56.25-73.75)
64.00 (55.00-74.00)
65.00 (57.00-71.00)
62.00 (53.00-69.00)
0.182
Systolic BP (mmHg, )
0.271
Diastolic BP (mmHg, median, Q1-Q3)
86.00 (78.25-98.75)
85.00 (78.00-95.50)
84.00 (78.00-94.00)
88.00 (79.00-100.25)
0.266
Total cholesterol (mmol/L, median, Q1-Q3)
4.50 (3.87-5.00)
4.64 (4.21-5.37)
4.48 (4.20-4.93)
4.80 (4.08-5.40)
0.521
Triglyceride (mmol/L, median, Q1-Q3)
1.39 (0.98-1.99)
1.44 (1.11-1.97)
1.80 (1.21-2.45)
1.67 (1.36-2.76)
0.009
HDL cholesterol (mmol/L, median, Q1-Q3)
1.12 (0.93-1.31)
1.09 (0.94-1.28)
1.02 (0.91-1.15)
1.03 (0.95-1.17)
0.107
LDL cholesterol (mmol/L, median, Q1-Q3)
2.51 (2.09-3.20)
2.60 (2.25-3.40)
2.64 (2.39-2.98)
2.70 (2.25-3.21)
0.772
Creatinine (μmol/L, median, Q1-Q3)
66.00 (54.00-75.00)
69.00 (60.00-85.00)
76.00 (67.00-88.00)
87.50 (70.00-104.00)
<0.001
Urea nitrogen (μmol/L, median, Q1-Q3)
5.42 (4.56-6.46)
5.45 (4.59-6.32)
5.51 (4.41-6.45)
5.33 (4.39-6.37)
0.944
Homocysteine (μmol/L, median, Q1-Q3)
11.64 (8.90-14.28)
12.00 (9.87-14.61)
12.91 (10.40-15.30)
13.05 (10.87-16.91)
0.015
Sex (, %)
<0.001
Male
27 (46.55%)
38 (64.41%)
39 (68.42%)
53 (82.81%)
Female
31 (53.45%)
21 (35.59%)
18 (31.58%)
11 (17.19%)
Hypertension (, %)
0.337
No
25 (43.10%)
24 (40.68%)
16 (28.07%)
26 (40.62%)
Yes
33 (56.90%)
35 (59.32%)
41 (71.93%)
38 (59.38%)
Diabetes (, %)
0.994
No
49 (84.48%)
50 (84.75%)
48 (84.21%)
55 (85.94%)
Yes
9 (15.52%)
9 (15.25%)
9 (15.79%)
9 (14.06%)
Coronary artery disease (, %)
0.096
No
46 (79.31%)
54 (91.53%)
53 (92.98%)
57 (89.06%)
Yes
12 (20.69%)
5 (8.47%)
4 (7.02%)
7 (10.94%)
Smoking (, %)
0.013
No
45 (77.59%)
44 (74.58%)
35 (61.40%)
34 (53.12%)
Yes
13 (22.41%)
15 (25.42%)
22 (38.60%)
30 (46.88%)
Drinking (, %)
0.111
No
53 (91.38%)
44 (74.58%)
46 (80.70%)
50 (78.12%)
Yes
5 (8.62%)
15 (25.42%)
11 (19.30%)
14 (21.88%)
NIHSS
<0.001
Minor stroke ()
28 (48.28%)
40 (67.80%)
50 (87.72%)
55 (85.94%)
Moderate to severe stroke ()
30 (51.72%)
19 (32.20%)
7 (12.28%)
9 (14.06%)
Note: the continuous variable of nonnormal distribution is calculated by Kruskal-Wallis H test. BP: blood pressure; HDL: high-density lipoprotein; LDL: low-density lipoprotein; UA: uric acid; NIHSS: National Institutes of Health Stroke Scale.
