Research Article

Miniaturized Water-Jet Ultrasound Indentation System for Quantitative Assessment of Articular Cartilage Degeneration: A Validation Study

Table 1

Change of measured parameters before and after enzymatic digestions.

ParametersEnzymeBefore treatmentAfter treatmentChange

Thickness (mm)Trypsin
Collagenase
IRC (dB)Trypsin]
Collagenase
Stiffness (MPa)Trypsin]
Collagenase
(MPa)Trypsin]
Collagenase
EDRWJ (%)Trypsin]
Collagenase
EDRRI (%)Trypsin
Collagenase

Values are expressed as (SD). IRC: integrated reflection coefficient, E: Young’s modulus, EDR: energy dissipation ratio, WJ: water-jet, RI: Rigid indentation. Level of significance of change compared to pretreatment or comparison of changes between the two types of enzymatic digestion: , .