Research Article
Acacetin Suppresses IL-1β-Induced Expression of Matrix Metalloproteinases in Chondrocytes and Protects against Osteoarthritis in a Mouse Model by Inhibiting NF-κB Signaling Pathways
Figure 1
Safranin O/fast green staining and expression of matrix metalloproteinases (MMPs) in cartilage samples from controls and patients with OA. (a) X-rays of hip joints and Safranin O/fast green staining of control and OA cartilage samples. . (b) The relative mRNA expression of MMP-1, MMP-3, and MMP-13 in control and OA cartilage tissues. (c) The protein expression of MMP-1, MMP-3, and MMP-13 in control and OA cartilage tissues. (d) Immunohistochemical staining of cartilage tissues from OA and control patients for MMP-1, MMP-3, and MMP-13. (e) Percentages of MMP-1-, MMP-3-, and MMP-13-positive cells in control and OA cartilage samples. , , and . .
(a) |
(b) |
(c) |
(d) |
(e) |