Research Article
Nrp-1 Mediated Plasmatic Ago2 Binding miR-21a-3p Internalization: A Novel Mechanism for miR-21a-3p Accumulation in Renal Tubular Epithelial Cells during Sepsis
Figure 1
miR-21a-3p and Ago2 levels of both TECs and plasma during sepsis. (a) Quantitative analysis of RT-PCR results of miR-21a-3p of either plasma or TECs at different time points. (b) Quantitative analysis of ELISA for Ago2 concentrations of plasma at different groups. (c) Representative RIP results of Ago2 binding miR-21a-3p in plasma of different groups. (d) Representative Western Blot results of Ago2 in TECs of the control group and CLP groups at different time points ( vs. the control; Ctrl: control; 12 h: 12 hours after CLP; 18 h: 18 hours after CLP; 24 h: 24 hours after CLP).
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