Identification of Functional Genes in Pterygium Based on Bioinformatics Analysis

Figure 1

The differentially expressional pattern of RNAs from pterygium and control conjunctiva. (a–d) Volcano plots of DELs, DEMis, and DEMs: (a) DELs (GSE83627); (b) DEMis (GSE21346); (c) DEMs (GSE51995); (d) DEMs (GSE2513). Each point indicates an RNA. Green dots denote the downregulated RNAs, red points represent the upregulated RNAs under the same thresholds, and gray points indicate RNAs that did not change significantly. The criteria are based on and values <0.05. (e–h) Heat maps of DERNAs (e) DELs (GSE83627), (f) DEMis (GSE21346), (g) DEMs (GSE51995), and (h) DEMs (GSE2513). Each column represents one sample, and each row refers to an RNA. The color legend is on the top-right of the figure. Green indicates RNAs with a lower expression relative to the geometrical means; red indicates genes with a greater expression relative to the geometrical means. DELs represent differentially expressed long noncoding RNAs; DEMis represent differentially expressed microRNAs; DEMs represent differentially expressed mRNAs.

(a)

(b)

(c)

(d)

(e)

(f)

(g)

(h)