Research Article

Epidural Labor Analgesia Is Associated with a Decreased Risk of the Edinburgh Postnatal Depression Scale in Trial of Labor after Cesarean: A Multicenter, Prospective Cohort Study

Table 2

Perinatal variables of parturients who completed the study for TOLAC.

VariableTOLAC (CTRL)TOLAC (EXP)Statistical value value
N (all)N (%) or mean ± SDN (all)N (%) or mean ± SD

Mode of delivery160263<0.001
 VBAC111 (69.38%)225 (85.55%)
 Cesarean49 (30.63%)38 (14.45%)

Instrumental delivery in VBAC27431
 Vacuum extraction15 (13.51%)23 (10.22%)
 Forceps12 (10.81%)20 (8.89%)

Episiotomy14942 (28.19%)256111 (43.36%)0.003

Perineum/Cervical laceration14970 (46.98%)255106 (41.57%)0.3

Uterine rupture1600 (0%)2630 (0%)1

Estimated blood loss after delivery (mL)1542601
 ≤500151 (98.05%)255 (98.08%)
 >5003 (1.95%)5 (1.92%)

Labor duration in VBAC
 The first labor duration (min)108334.14 ± 225.94221526.93 ± 266.856050.5<0.001
 The second labor duration (min)10228.09 ± 31.6221746.14 ± 32.645836<0.001
 The third labor duration (min)1088.62 ± 3.872229.43 ± 5.0311211.50.294
Initiating lactation period (hours)15711 ± 132627 ± 1224276.50.002

VAS pain at epidural (cm)
 T0: time 0996.34 ± 2.162198.20 ± 1.195191.5<0.001
 T1: PCEA after 30 min1007.00 ± 2.162170.94 ± 1.6121103<0.001
 T2: cervical:6 cm1007.67 ± 2.332111.09 ± 1.7120404.5<0.001
 T3: cervical:10 cm998.64 ± 2.132101.78 ± 2.0020213<0.001
 T4: immediate delivery of the fetus971.65 ± 2.442091.88 ± 1.6080620.002

Feeding patterns within 48 hours1582330.361
 Breast152 (96.20%)218 (93.56%)
 Milk6 (3.80%)15 (6.44%)

Feeding amounts within 48 hours1472300.491
 Normal137 (93.20%)219 (95.22%)
Discomfort within 42 days15933 (20.75%)25628 (10.94%)0.007

EPDS score 48 hours<0.001
 <10117117 (73.58%)237237 (91.51%)
 ≥104242 (26.42%)2222 (8.49%)

EPDS score 42 days<0.001
 <10119119 (74.84%)241241 (93.41%)
 ≥104040 (25.16%)1717 (6.59%)

Comparisons were made using Student’s t-test or Wilcoxon rank sum test for nonnormally distributed variables. Comparisons were made using Pearson’s chi-squared test and Fisher’s exact test for proportions.