Association of Tumor Necrosis Factor Receptor 1 Promoter Gene Polymorphisms (-580 A/G and -609 G/T) and TNFR1 Serum Levels with the Susceptibility to Gastric Precancerous Lesions and Gastric Cancer Related to H. pylori Infection in a Moroccan Population

Table 2

Association between sTNFR1 serum levels and gastric lesion severity.

sTNFR1 (pg/mL)	HC	CG	PL	GC
Mean	779.8	881.3	892.6	929.9
Median	780	881	921	881
SD	105.1	158	154.6	196.7
Range	540-958	622-1257	520-1132	633-1439
value significance intragroups	0.000018
value significance intergroups
Case vs. controls		0.0003	0.00003	0.0002
Case vs. chronic gastritis		—	0.36	0.28
Case vs. precancerous lesions		—	—	0.61

HC: healthy controls; CG: chronic gastritis; PL: precancerous lesions; GC: gastric cancer; : Kruskal-Wallis test; : Wilcoxon test.