Trifolium Flavonoids Overcome Gefitinib Resistance of Non-Small-Cell Lung Cancer Cell by Suppressing ERK and STAT3 Signaling Pathways

<div>TF inhibited phosphorylation of STAT3 and ERK in PC-9R cells. (a) PC-9R cells were treated with indicated doses of TF for 24 h. Proteins were extracted and subjected to Western blotting assay to evaluate phosphorylation of STAT3, AKT, and ERK. (b) Quantitative analysis expression of proteins in (a). 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BioMed Research International

fig5

Figure 5

Figure 5: Trifolium Flavonoids Overcome Gefitinib Resistance of Non-Small-Cell Lung Cancer Cell by Suppressing ERK and STAT3 Signaling Pathways 