Research Article
Genomic Analysis Reveals Novel Specific Metastatic Mutations in Chinese Clear Cell Renal Cell Carcinoma
Table 2
Genes with different mutated frequencies in ccRCC with or without metastasis.
| Gene | Metastasis () | Nonmetastasis () | value | Samples with mutation | Samples without mutation | Samples with mutation | Samples without mutation | |
| TOP1 | 3 | 14 | 0 | 89 | 0.004 | SNCAIP | 3 | 14 | 0 | 89 | 0.004 | PBRM1 | 0 | 17 | 24 | 65 | 0.011 | PRDM1 | 2 | 15 | 0 | 89 | 0.024 | CDKN1A | 2 | 15 | 0 | 89 | 0.024 | SMAD4 | 2 | 15 | 1 | 88 | 0.066 | PTK2 | 2 | 15 | 1 | 88 | 0.066 | LATS2 | 2 | 15 | 1 | 88 | 0.066 | KDM6A | 2 | 15 | 1 | 88 | 0.066 | TCF3 | 2 | 15 | 2 | 87 | 0.120 | WRN | 1 | 16 | 0 | 89 | 0.160 | TGFBR1 | 1 | 16 | 0 | 89 | 0.160 | TEK | 1 | 16 | 0 | 89 | 0.160 | TCF7L2 | 1 | 16 | 0 | 89 | 0.160 | SPOP | 1 | 16 | 0 | 89 | 0.160 |
|
|