Porcupine Inhibitor LGK974 Downregulates the Wnt Signaling Pathway and Inhibits Clear Cell Renal Cell Carcinoma

Figure 2

PORCN is coexpressed with Wnt protein and plays a role through Wnt signaling pathway. (a) Protein-protein interaction of PORCN and its related genes with Wnt signaling pathway-related proteins, apoptosis-related proteins, and EMT-related proteins. (b) PORCN and its related genes in the Wnt signaling pathway. (c) The coexpression of PORCN and Wnt proteins. (d–f) KEGG (d), Panther (e), and Reactome (f) pathway analysis of PORCN and its 30 most related genes.

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