Quantitative Assessment of Blood Lactate in Shock: Measure of Hypoxia or Beneficial Energy Source

Figure 4

Summary of measurements of lactate turnover versus blood lactate in dogs reported by Daniel et al. and Eldridge (see main text for references). All of the points represent individual dogs with the turnover estimated using the steady state tracer method. The black points represent normal controls, without (circles or stars) or with lactate infusion (squares or pentagons) to increase the blood concentration. The yellow points are the measurements of Daniel et al. for septic, cardiac tamponade, and hemorrhagic-induced shock, and the red points are the hemorrhagic shock results of Eldridge. The green points are for various levels of exercise, either without (circles) or with (squares) lactate infused to increase the blood concentration. The dashed line shows the predicted relationship if the clearance has a constant value of 2.0 L/min/70 kg.