Quantitative Assessment of Blood Lactate in Shock: Measure of Hypoxia or Beneficial Energy Source

Table 3

Contributions of individual organs to the total basal resting postprandial human lactate uptake () and release () in units of mmole/min. The gut value is extrapolated from the dog, all the rest are for human. If there are no tracer measurements, then only the net value is used for either or , which are then a minimum estimate (indicated by the ≥ symbol), and it is assumed that there is no flux in the opposite direction (indicated by the ?? symbol). The net organ flux is listed in the last column (+ indicates net uptake, - indicates net release).

Organ	Reference	Uptake	Release	Net
Heart	[169]	0.067	0.025	+0.042
Brain	[64]	0.1	0.15	-0.05
Skeletal muscle	[64, 93, 170]	0.3	0.4	-0.1
Kidney	[29]	≥0.16	0^??	+0.16
Liver	(See text)	≥0.28	0^??	+0.28
Gut	(See text)	0^??	≥0.085	-0.085
Adipose	[171–173]	0^??	≈0.2	-0.2
Erythrocytes	(See text)	0	0.105	-0.105
Total		≥0.91	≥1.08	-0.056