Identification of the Functional Domain of HPIV3 Matrix Protein Interacting with Nucleocapsid Protein

Figure 5

The 143-182aa in the M is the key region that encapsulates the N into the VLP. (a) N-Myc, HA-M, and MΔN143-182 plasmids were transfected alone or cotransfected into 293T cells. After transfection, cells and VLPs were collected and protein expression was detected by WB. (b) The relative ability of M and MΔN143-182 to encapsulate N into VLP. Data are from the average of three independent experiments, .

(a)

(b)