Research Article

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and Polychlorinated Biphenyl Coexposure Alters the Expression Profile of MicroRNAs in the Liver Associated with Atherosclerosis

Figure 3

TCDD and Aroclor1254 co-exposure-regulated miRNAs and their association with diseases. TCDD and Aroclor1254 co-exposure-induced up- or downregulated (more than 1.5-fold change) miRNAs were analyzed using IPA software and the database (Ingenuity Systems Inc.). The data presented in the graph were various pathways regulated by TCDD- and Aroclor1254-coinduced miRNAs. The -axis represented the number of miRNAs involved in pathways.