Exosomal miRNA-215-5p Derived from Adipose-Derived Stem Cells Attenuates Epithelial–Mesenchymal Transition of Podocytes by Inhibiting <i>ZEB2</i>

<div>Exploration of the role of ADSCs-Exos on HG-induced migration of MPC5 cells. (a) MPC5 cells were incubated with sterile serum from control and DN patients supplemented with or without ADSCs-Exos, and then, cell viability was measured by CCK8 assay. (b) Representative images of migration cells as evaluated by Transwell assay in HG-induced MPC5 cells treated with NG, MA, HG, and ADSCs-Exos. (c) The number of migratory cells was counted by ImageJ software in HG-induced MPC5 cells treated with NG, MA, HG, and ADSCs-Exos. (d) Photograph of cellular damage in different groups was observed by a biological microscope. 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BioMed Research International

fig1

Figure 1

Figure 1: Exosomal miRNA-215-5p Derived from Adipose-Derived Stem Cells Attenuates Epithelial–Mesenchymal Transition of Podocytes by Inhibiting <i>ZEB2</i> 

BioMed Research International

Exosomal miRNA-215-5p Derived from Adipose-Derived Stem Cells Attenuates Epithelial–Mesenchymal Transition of Podocytes by Inhibiting ZEB2

Figure 1