Analysis of Segmental Lymph Node Metastasis and Clinical Features in cT1N0M0 Lung Adenocarcinoma

Table 3

Univariate analysis of iLSN metastases in 200 cases.

Influence factor	Without iLSN metastasis (n = 186)	With iLSN metastasis (n = 14)	t/χ^2	value
Age (years)	58.94 ± 7.37	57.93 ± 3.38	0.955	0.349
Gender			1.063	0.302
Male	93 (50.0)	9 (64.3)
Female	93 (50.0)	5 (35.7)
Serum Cyfra 21-1 level			0.000	1.000
≤3.3 ng/ml	156 (83.9)	12 (85.7)
>3.3 ng/ml	30 (16.1)	2 (14.3)
Serum NSE level			2.984	0.084
≤16.30 ng/ml	84 (45.2)	3 (21.4)
>16.30 ng/ml	102 (54.8)	11 (78.6)
Serum CEA level			5.88	0.015
≤4.5 ng/ml	146 (78.5)	7 (50.0)
>4.5 ng/ml	40 (21.5)	7 (50.0)
Tumor size			54.736	<0.001
0–1	94 (50.5)	1 (7.1)
1–2	76 (40.9)	2 (14.3)
2–3	16 (8.6)	11 (78.6)
SUVmax			8.522	0.004
<2.5	114 (61.3)	3 (21.4)
≥2.5	72 (38.7)	11 (78.6)
Imaging features			19.683	<0.001
Pure GGN	124 (66.7)	1 (7.1)
Nonpure GGN	62 (33.3)	13 (92.9)
Pathological subtype			12.771	<0.001
Other IA	69 (37.1)	12 (85.7)
AIS/MIA/LPA	117 (62.9)	2 (14.3)
N1 lymph nodes metastasis			14.312	<0.001
No	153 (82.3)	5 (35.7)
Yes	33 (17.7)	9 (64.3)