Triggering of Apoptosis in Osteosarcoma 143B Cell Line by Carbon Quantum Dots via the Mitochondrial Apoptotic Signal Pathway

<div>The antitumor effects and the biosafety of CQDs in vivo. (a) Body weight of tumor-bearing mice after treatment with CQDs or physiological saline for 4 weeks. (b) Image of the dissected subcutaneous tumors from the tumor-bearing mice receiving CQDs treatment. (c) BALB/c mice body weight after treatment with CQDs or physiological saline for 12 weeks. (d) Complete blood panel tests and blood chemistry analysis of BALB/c mice after treatment with CQDs for 4 and 12 weeks. (e) Images of H&amp;E-stained organ samples from mice sacrificed at 12 weeks after gastric perfusion of CQDs. Images were captured at 400x magnification. 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BioMed Research International

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Figure 4

Figure 4: Triggering of Apoptosis in Osteosarcoma 143B Cell Line by Carbon Quantum Dots via the Mitochondrial Apoptotic Signal Pathway 