miR193b Promotes Apoptosis of Gastric Cancer Cells via Directly Mediating the Akt Pathway

Figure 1

miR193b acts as a tumor suppressor by promoting apoptosis of GC cells. (a) miR193b levels in the normal epithelial cell line GES-1 and the gastric cancer cell lines AGS, N87, SNU-16, BGC-823, and SGC-7901. (b) The relative expression of miR193b in gastric normal tissues and matching cancer tissues (). Data represent the median flanked by the 25th and 75th percentiles. (c) miR193b expression of 44 pairs of GC and normal tissues (original data were extracted from TCGA GC dataset). (d) Patients with high TNM stage show lower miR193b expression (original data were extracted from TCGA GC dataset). and were calculated using Student’s -test.

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