Research Article
The Predictive Value of Serum Uric Acid on Acute Kidney Injury following Traumatic Brain Injury
Table 1
Baseline characteristics of AKI patients and non-AKI patients.
| | Total () | Non-AKI () | AKI () | |
| | Age (year) | 43 (25-57) | 41 (23-54) | 47 (32-60) | 0.010 | | Female (, %) | 93 (24.87) | 76 (25.76%) | 17 (21.52%) | 0.433 | | Prehospital time (hour) | 1 (1-2) | 1 (1-2) | 1 (1-1) | 0.028 | | Vital signs in admission | | | | | | SBP (mmHg) | 120 (105-138) | 120 (106-138) | 113 (102-133) | 0.135 | | DBP (mmHg) | | | | 0.104 | | Heart rate (bpm) | 100 (81-119.25) | 98 (80-117) | 107 (89-124) | 0.015 | | Temperature (°C) | 36.7 (36.5-37.1) | 36.7 (36.5-37) | 36.8 (36.4-37.5) | 0.368 | | Respiratory rate | 20 (16-22) | 20 (16-23) | 18 (15-22) | 0.022 | | GCS in admission | 6 (5-9) | 7 (5-10) | 5 (4-6) | <0.001 | | Shock (%) | 116 (31.02%) | 71 (24.07%) | 45 (56.96%) | <0.001 | | Laboratory tests | | | | | | WBC (109/L) | 14.34 (10.33-19) | 13.98 (10.35-18.92) | 14.98 (10.15-20.17) | 0.607 | | Platelet (109/L) | 106.5 (68-171.25) | 122 (76-180) | 72 (44-111) | <0.001 | | Hemoglobin (g/L) | 90 (76-110.25) | 94 (79-112) | 80 (71-96) | <0.001 | | Albumin (g/L) | | | | <0.001 | | Glucose (mmol/L) | 9.49 (7.04-13.14) | 8.84 (6.68-12.53) | 11.7 (8.9-16.77) | <0.001 | | Chlorine (mmol/L) | 110.9 (105.58-118.93) | 109.3 (104.3-116.6) | 116.9 (111.8-128.9) | <0.001 | | Cholesterol (mmol/L) | 2.75 (1.97-3.62) | 2.89 (2.22-3.68) | 1.97 (1.35-2.79) | <0.001 | | Total bilirubin (μmol/L) | 14.6 (10.1-20.35) | 13.9 (9.4-19.65) | 17.5 (12.1-22.7) | 0.001 | | Serum urea (mmol/L) | 6.36 (4.93-8.64) | 5.93 (4.65-7.77) | 9.4 (7.11-15.3) | <0.001 | | Serum creatinine (μmol/L) | 71 (51-96.25) | 65 (48-82) | 133 (97-237) | <0.001 | | Uric acid (μmol/L) | 288 (186.75-388.5) | 249 (165-347) | 452.5 (360-585) | <0.001 | | Drugs for reducing ICP | | | | | | Hypertonic saline (%) | 91 (24.33%) | 81 (27.46%) | 10(12.66%) | 0.004 | | Mannitol (%) | 257 (68.72%) | 203 (68.81%) | 54 (68.35%) | 0.938 | | Glycerol fructose (%) | 30 (8.02%) | 23 (7.80%) | 7 (8.86%) | 0.760 | | Furosemide (%) | 55 (14.71%) | 39 (13.22%) | 16 (20.25%) | 0.129 | | In-hospital mortality (%) | 187 (50%) | 119 (40.34%) | 68 (80.08%) | <0.001 | | 90-day GOS | 2 (1-3) | 3 (1-4) | 1 (1-1) | <0.001 | | Length of ICU stay (day) | 2 (1-16) | 2 (0-17) | 2 (1-11) | 0.384 | | Length of hospital stay (day) | 11 (4-27) | 13 (5-28) | 6 (3-14) | 0.001 |
|
|
