Research Article

Respiratory Muscle Training Improves Functional Outcomes and Reduces Fatigue in Patients with Myasthenia Gravis: A Single-Center Hospital-Based Prospective Study

Table 3

Comparison of MG outcomes and fatigue score before and after RMT.

RMT group ()Disease control group ()
BaselineFollow-up valueBaselineFollow-up value

Outcome measures
 QMG score9.5 [5.5, 12.75]7.5 [4, 12]0.0212.5 [4.75, 14.75]9.5 [5.5, 13.25]0.11
 MGC scale4 [1.25, 6.75]2 [0.25, 3]0.053.5 [0, 8]3.5 [0.75, 4.75]0.26
Fatigue scale
 MFSI_SF_general7 [5.0, 10.75]7 [6.0, 8.75]0.546 [4.75, 8.25]8 [5.75, 11.75]0.21
 MFSI_SF_physical8 [5.25, 8.75]5 [3.0, 8.0]0.027 [4.75, 9.75]8.5 [5.75, 11.75]0.12
 MFSI_SF_emotion6 [3.25, 7.0]4 [3, 8.75]0.465 [3, 8.25]7 [4, 8.25]0.63
 MFSI_SF_mental6.5 [6.0, 8.0]7 [3.5, 8.75]0.876 [5.75, 9.5]7.5 [6, 11]0.29
 MFSI_SF_vigor10 [8.0, 13.75]11.5 [10, 13]0.1615 [11.5, 15.75]11 [6, 15.25]0.50
 MFSI_SF_total14 [5, 23.5]13 [1.25, 22]0.049 [0.75, 25.75]21.5 [6, 34.75]0.09

QMG: quantitative myasthenia gravis; MGC: myasthenia gravis composite; MFSI-SF: Multidimensional Fatigue Symptom Inventory-Short Form; RMT: respiratory muscle training. Significant difference () between follow-up and baseline.