Research Article
Differences in the Clinical Characteristics of Early- and Late-Onset Asthma in Elderly Patients
Table 1
Difference in demographics and comorbidities between EOA and LOA in elderly subjects
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| Variables | Total (n = 176) | EOA (n = 92) | LOA (n = 84) | value |
| Age | 70.98 ± 6.49 | 70.3 ± 77.10 | 71.65 ± 5.702 | 0.001 | Female | 94 (53.4%) | 51 | 43 | 0.573 | Rural region | 64 (36.4%) | 31 | 33 | 0.441 | Smoking status | Never | 104 (59.1%) | 60 | 44 | 0.084 | Former | 41 (23.3%) | 20 | 21 | 0.609 | Current | 31 (19.3%) | 12 | 19 | 0.096 | BMI, kg/m2 | 22.57 ± 2.43 | 22.31 ± 2.27 | 22.85 ± 2.58 | 0.140 | FH asthma | 78 (44.4%) | 48 | 30 | 0.028 | Atopy | 42 (23.9%) | 28 | 14 | 0.032 | Allergic rhinitis | 76 (43.8%) | 48 | 28 | 0.012 | Allergic eczema | 50 (26.9%) | 32 | 18 | 0.050 | COPD | 38/29 (21.6%) | 13/10 | 25/19 | 0.012 | Bronchiectasis | 36 (20.5%) | 18 | 18 | 0.760 | CVD | 51 (29.0%) | 28 | 23 | 0.656 | Depression | 13 (7.4%) | 7 | 6 | 0.906 | Anxiety | 56 (31.8%) | 33 | 23 | 0.227 | IgE | 118.41 ± 84.44 | 151.27 ± 99.22 | 82.43 ± 41.64 | 0.001 | FeNO, mean (SD) ppb | 38.64 ± 17.98 | 45.58 ± 21.85 | 31.05 ± 6.83 | 0.001 | Controlled | 61 (34.7%) | 30 | 31 | 0.550 | Uncontrolled | 47 (26.7%) | 26 | 21 | 0.625 | Partly controlled | 68 (38.6%) | 36 | 32 | 0.888 | Asthma severity | Mild | 58 (33.0%) | 30 | 28 | 0.919 | Moderate | 78 (44.3%) | 44 | 41 | 0.252 | Severe | 30 (17.0%) | 18 | 15 | 0.784 | Medications | Number on ICS/LABA | 153 (86.9%) | 81 | 72 | 0.647 | Number on high-dose ICS/LABA | 32 (18.2%) | 11 | 21 | 0.025 | Number on LAMA | Maintenance oral prednisolone | 7 (4.0%) | 4 | 3 | 0.792 | Maintenance oral theophylline | 47 (26.7%) | 20 | 27 | 0.119 | Unscheduled doctor visit in past one year | 45 (25.6%) | 25 | 20 | 0.609 | ED (<24 h) in past one year | 41 (23.3%) | 23 | 18 | 0.576 | Hospitalizations (>24 h) in past one year | 36 (20.5%) | 19 | 17 | 0.946 | History of intubation | 15 (8.5%) | 8 | 7 | 0.931 |
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All parametric data are expressed as mean (standard deviation) unless stated otherwise. |