Structure-Activity Relationship (SAR) and <i>in vitro</i> Predictions of Mutagenic and Carcinogenic Activities of Ixodicidal Ethyl-Carbamates

<table class="table-group" id="tab1"><tr><td><table class="table"><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr class="thead"><td class="align_left"></td><td class="align_center">LQM 919<br/>Ethyl (4-bromophenyl) carbamate</td><td class="align_center">LQM 996<br/>Ethyl (4-chlorophenyl) carbamate</td></tr><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr><td class="align_left">Chemical structure</td><td class="align_center"><object data="https://static.hindawi.com/articles/bmri/volume-2020/2981681/figures/2981681.tab-inline.001.svgz" name="2981681.tab-inline.001" type="image/svg+xml"></object></td><td class="align_center"><object data="https://static.hindawi.com/articles/bmri/volume-2020/2981681/figures/2981681.tab-inline.002.svgz" name="2981681.tab-inline.002" type="image/svg+xml"></object></td></tr><tr><td class="align_left">Molecular weight</td><td class="align_center">244</td><td class="align_center">199.63</td></tr><tr><td class="align_left">SMILES</td><td class="align_center">CCOC(=O)Nc1ccc(Br)cc1</td><td class="align_center">CCOC(=O)Nc1ccc(cl)cc1</td></tr><tr><td class="align_left">Descriptors</td><td class="align_center">Log Kow 3.13</td><td class="align_center">Log Kow 2.89</td></tr><tr class="table-tr"><td colspan="3"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>Nomenclature, chemical structure and characteristics of ethyl-carbamates.</div>

BioMed Research International

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Table 1

Table 1: Structure-Activity Relationship (SAR) and <i>in vitro</i> Predictions of Mutagenic and Carcinogenic Activities of Ixodicidal Ethyl-Carbamates 

BioMed Research International

Structure-Activity Relationship (SAR) and in vitro Predictions of Mutagenic and Carcinogenic Activities of Ixodicidal Ethyl-Carbamates

Table 1