In Vitro Evaluation of Curcumin-Encapsulated Chitosan Nanoparticles against Feline Infectious Peritonitis Virus and Pharmacokinetics Study in Cats

Table 6

Log₁₀ copy number of virus and decrement percentages for 3’UTR log₁₀ copy number in samples treated for 24, 48 and 72 h.

Incubation time	Treatment	3UTR log10 copy number	% log10 copy number decrement
48 h	FIPV sample	^e	^a
	Curcumin 5 μM	^d	^b
	Cur-CS 5 μM	^d	^c
	Curcumin 10 μM	^cd	^c
	Cur-CS 10 μM	^bc	^d
	Curcumin 20 μM	^b	^e
	Cur-CS 20 μM	^a	^f
72 h	FIPV sample	^d	^a
	Curcumin 5 μM	^cd	^b
	Cur-CS 5 μM	^bcd	^b
	Curcumin 10 μM	^abc	^cd
	Cur-CS 10 μM	^ab	^cd
	Curcumin 20 μM	^abc	^c
	Cur-CS 20 μM	^a	^d

Data are presented as () and analysed using one-way ANOVA and post hoc Duncan multiple test. For each time interval and parameter, means within a column of determined incubation time (48 and 72 h) with different roman letters were significantly different () from each other. Cur-CS: curcumin-encapsulated chitosan; FIPV: feline infectious peritonitis virus.