In Vitro Evaluation of Curcumin-Encapsulated Chitosan Nanoparticles against Feline Infectious Peritonitis Virus and Pharmacokinetics Study in Cats

Table 8

Measurement of immune-related protein concentrations (pg/mL) of different treatment groups in infected cells at 48 h.

Cytokine/chemokine	Uninfected control cells	Infected cells	Infected cells treated with curcumin	Infected cells treated with Cur-CS nanoparticles
PDGF-BB	^a	^b	^a	^a
IL-6	<37.42			<39.42
IL-8	^a	^c	^b	^a
KC	^a	^d	^c	^b
SDF-1	^a	^b	^a	^a
RANTES	^a	^c	^b	^b
MCP-1	^a	^b	^a	^a
TNFα	^a	^b	^a	^a

Data are presented as where each experiment was performed in duplicate and analysed using one-way ANOVA and post hoc Duncan multiple test. For each cytokine/chemokine, means within a row with different roman letters were significantly different () from each other. Mean with an asterisk () was significantly () different from the positive control (infected cells). Cur-CS: curcumin-encapsulated chitosan.