BioMed Research International / 2020 / Article / Tab 9

Research Article

In Vitro Evaluation of Curcumin-Encapsulated Chitosan Nanoparticles against Feline Infectious Peritonitis Virus and Pharmacokinetics Study in Cats

Table 9

Pharmacokinetic parameters of curcumin and Cur-CS nanoparticles given s.i.d. and b.i.d. orally in healthy cats.

FormulationCurcuminCur-CS nanoparticles

Single dosing (s.i.d.)
(ng/mL)
(h)34
AUC0-12 (ng/mL h)
AUC0-∞ (ng/mL h)
Two dosing (b.i.d.)
(ng/mL)
(h)44
AUC0-12 (ng/mL h)
AUC0-24 (ng/mL h)

Data are presented as () and analysed using paired sample -test. For each parameter, means with an asterisk () were significantly () different from the control (curcumin). Cur-CS: curcumin-encapsulated chitosan.

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