The Impact of Bioactive Surfaces in the Early Stages of Osseointegration: An In Vitro Comparative Study Evaluating the HAnano® and SLActive® Super Hydrophilic Surfaces

Figure 3

HAnano® stimulates osteogenic phenotype. Transcriptional profile determination of (a) Otx, (b) Runx2, (c) Caspase1, and (d) Alp in osteoblasts subjected to implants up to 72 h by qPCR technology. The relative gene expression levels were determined using the cycle threshold (Ct) method and showed in a graphical format with normalized values as a function of the control assigned value 1. The results represented as of three independent experiments. and when compared to Ctrl and when compared to SLActive®.

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