Prevalence and Risk Factors of Cytopenia in HIV-Infected Patients before and after the Initiation of HAART

Table 5

The risk factors of cytopenia with persistent cytopenia after 24 months HAART.

	df	Univariate analysis, OR (95% CI)	value	Multivariate analysis, OR (95% CI)	value
AZT	1
No		Ref	—	Ref	—
Yes		4.89 (1.49, 16.07)	0.009	3.71 (1.16, 11.9)	0.009
Sex	1
Male		Ref	—	Ref	—
Female		5.42 (2.35, 12.5)	<0.001	5.54 (2.47, 12.42)	<0.001
HBV-coinfection	1
No		Ref	—	Ref	—
Yes		3.8 (1.05, 13.95)	0.042	4.84 (1.47, 15.91)	0.01
CD4^+T-cell counts at baseline	1
≥200		Ref	—	Ref	—
<200		2.47 (1.04, 5.85)	0.04	2.42 (1.2, 4.86)	0.013
CD4^+ T-cell counts at 24 months of HAART	1
≥200		Ref	—
<200		0.58 (0.23, 1.48)	0.257
WHO stage at baseline	3		0.4
I		Ref	—
II		1.13 (0.51, 2.5)	0.77
III		4.37 (0.93, 20.54)	0.124
IV		0.72 (0.12, 4.21)	0.72
Age	1
<40		Ref	—
≥40		0.97 (0.44, 2.15)	0.93
D4T	1
No		Ref	—
Yes		1.4 (0.72, 2.73)	0.32
HCV-coinfection	1
No		Ref	—
Yes		1.01 (0.1, 9.96)	0.993

Note: df, degree of freedom; WHO, World Health Organization; BMI, body mass index; Ref, reference; D4T, stavudine; AZT, zidovudine.