BioMed Research International / 2020 / Article / Tab 1

Review Article

Low-Frequency Repetitive Transcranial Magnetic Stimulation for the Treatment of Chronic Tinnitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Table 1

Characteristics of included studies on repetitive transcranial magnetic stimulation for tinnitus in the meta-analysis.

StudyGroups()Gender (male/female)Age (years)PatientsStimulation locationParametersTreatment durationFollow-upMeasurement

Anders 2010, [21]Real: 26
Sham: 26
Real: 12/10
Sham: 17/3
Real:
Sham:
monthsLeft primary auditory cortex1 Hz, 110% RMT, 1500 pulses2 weeksPosttreatment, 1 month, 6 monthsTHI, TQ, VAS
Marcondes 2010, [20]Real: 10
Sham: 9
Not reported>18 years old monthsLeft temporoparietal cortex1 Hz, 110% RMT, 1020 pulses5 days1 month, 6 monthsTHI
Langguth 2012, [19]Real: 96
Sham: 45
Real: 67/29
Sham: 31/14
Real:
Sham:
monthsLeft temporal cortex1 Hz, 110% RMT, 2000 pulses2 weeksPosttreatment, 7 weeks, 11 weeksTQ
Barwood 2013, [18]Real: 4
Sham: 4
Real: 2/2
Sham: 2/2
Real:
Sham:
monthLeft primary auditory cortex1 Hz, 100% RMT, 2000 pulses2 weeks1 week, 1 month, 3 monthsTHI
Hoekstra 2013, [17]Real: 26
Sham: 24
Real: 26/0
Sham: 15/9
Real:
Sham:
monthsBilateral primary auditory cortex1 Hz, 110% RMT, 2000 pulses5 daysPosttreatment, 1 month, 6 monthsTHI, TQ, VAS
Folmer 2015, [16]Real: 32
Sham: 32
Real: 25/7
Sham: 26/6
Real:
Sham:
yearLeft or right auditory cortex1 Hz, 110% RMT, 2000 pulses2 weeksPosttreatmentTHI
Wang 2016, [22]Real: 14
Sham: 10
Real: 6/8
Sham: 3/10
Real:
Sham:
monthsLeft temporoparietal cortex1 Hz, 110%MT, 1000 pulses2 weeksPosttreatmentVAS
Landgrebe 2017, [12]Real: 71
Sham: 75
Real: 54/17
Sham: 51/24
Real:
Sham:
monthsLeft temporal cortex1 Hz,110% RMT, 2000 pulses2 weeksPosttreatment, 6 monthsTHI, TQ
Sahlsten 2017, [15]Real: 19
Sham: 20
27/12Real:
Sham:
monthsLeft auditory cortex1 Hz,100% RMT, 4000 pulses2 weeks1 week, 1 month, 6 monthsTHI, VAS
Kyong 2019, [14]Real: 16
Sham: 8
Real: 10/6
Sham: 6/2
Real:
Sham:
monthsTemporal cortex or the temporal and the frontal regions1 Hz,110% RMT, 3000 pulses2 weeksPosttreatmentTHI

Real = real group; sham = sham group; RMT = resting motor threshold; THI = Tinnitus Handicap Inventory; TQ = Tinnitus Questionnaire; VAS = visual analogue scale.

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