BioMed Research International / 2020 / Article / Tab 3

Research Article

Changes in the Clinical Characteristics of 62 Patients Who Died from Coronavirus Disease 2019

Table 3

Laboratory tests.

Routine blood testOn admission ()Last follow-up () value

Erythrocytes (×109; normal range: 3.5-5.0)4.22 (2.35-5.34)3.97 (2.23-5.4)0.325
Lymphocytes (×109; normal range: 0.8-4.0)0.77 (0.13-4.22)0.58 (0.16-3.38)0.023
Neutrophils (×109; normal range: 2.0-7.5)4.25 (3.11-7.86)3.56 (2.59-6.68)0.015
Platelets (×109; normal range: 100-300)203.5 (109.2-286.3)209.3 (110.9-265.3)0.214
Blood gas analysisOn admission ()Last follow-up ()
PH value (normal range: 7.35-7.45)7.37 (6.45-7.59)7.12 (6.23-7.47)0.042
PaCO2 (mmHg, normal range: 35-45)42.0 (29.0-56.0)48 (27.0-68.0)0.084
PaO2 (mmHg, normal range: 80-100)82.0 (55.0-95.0)65.0 (38.0-78.0)0.022
Lactic acid (mmol/L, normal range: 0.5-2.2)2.1 (0.8-10)3.5 (0.8-14.2)0.013
Coagulation functionOn admission ()Last time ()
Activated partial thromboplastin time (s; normal range:25-37)30.4 (22.3-45.5)36.7 (24.6-55.3)0.065
Prothrombin time (s; normal range: 11-14)11.6 (9.9-23.6)13.2 (11.2-43.9)0.054
D-dimer (mg/L; normal range: <0.2)1.58 (0.1-102.7)6.48 (0.35-463.2)0.001
Biochemical indicators
 Albumin (g/L; normal range: 38-48)32.6 (24.1-45.1), 27.9 (22.7-56.4), 0.034
 Alanine transaminase (U/L; normal range: 0-40)17.5 (4.4-1524), 225.6 (5.9-645.9), 0.001
 Creatinine (μmol/L; normal range: 50-120)66.4 (36.7-1422.5), 36.5 (35.2-1303), 0.001
 Blood urea nitrogen (mmol/L normal range: 3.1-9.5)5.37 (2.44-48.21), 8.26 (4.08-72.42), 0.026
 Cardiac troponin I (ng/mL; normal range: <0.1)0.025 (0.005-1.38), 0.04 (0.004-4.75), 0.001
Infection-related biomarkers
 Procalcitonin (ng/L; normal range: <0.5)0.47 (<0.05-7.16), 0.63 (0.06-100), 0.125
 C-reactive protein (mg/L; normal range: 0.8-8)2.55 (0.1->20), 4.68 (0.5->20), 0.034
 Interleukin-6 (pg/mL; normal range: 56.37-150.33)22.6 (2.21-92.9), 290.6 (24.42-684.3), <0.001

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