Prognostic Value of Serum Osteopontin in Acute Exacerbation of Idiopathic Pulmonary Fibrosis

Figure 1

Serum OPN and KL-6 levels in patients with stable IPF and in those with AE-IPF. (a) Serum OPN concentrations were elevated significantly in AE-IPF patients when compared with S-IPF patients and healthy controls by ELISA ( and , respectively). (b) Serum KL-6 levels increased obviously in AE-IPF patients compared with S-IPF patients and healthy controls ( and , respectively). AE-IPF, acute exacerbation of idiopathic pulmonary fibrosis; S-IPF, stable idiopathic pulmonary fibrosis; IPF, idiopathic pulmonary fibrosis. ; ; (Mann–Whitney U test).

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