Isoflurane Postconditioning Upregulates Phosphorylated Connexin 43 in the Middle Cerebral Artery Occlusion Model and Is Probably Associated with the TGF-β1/Smad2/3 Signaling Pathway

Figure 1

Effects of 1.5% ISPOC on neurological deficit scores and infarct volume on cerebral I/R injury. (a) Brain sections (2 mm thick) were stained with 2% TTC. The red-stained area indicates normal areas, and the pale area signifies ischemic areas of the brain tissue. TTC: 2,3,5-triphenyltetrazolium chloride. (b) Proportion of the brain infarct volume in the ipsilateral hemisphere. The results are expressed as (SEM) (). , . (c) Neurological deficit scores were assessed after middle cerebral artery occlusion (MACO) for 90 min and reperfusion for 24 h. The results are presented in a scatter plot format (). , .

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