Isoflurane Postconditioning Upregulates Phosphorylated Connexin 43 in the Middle Cerebral Artery Occlusion Model and Is Probably Associated with the TGF-<i>β</i>1/Smad2/3 Signaling Pathway

<div>Effects of 1.5% ISPOC, TGF-<i>β</i>1 inhibitor LY2157299, p-Cx43 inhibitor Ro318220, and p-Cx43 activator 18<i>β</i>-GA on the survival of hippocampal CA1 neurons after cerebral I/R injury in rats (HE staining). (a) Brain sections were stained with HE. Contraction of the nucleus and cellular edema showed the impaired neurons in the hippocampal CA1 area. Original magnification: 200x. Scale bars: 50 <i>μ</i>m. (b) Proportion of injured neurons in the CA1 area. 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BioMed Research International

fig2

Figure 2

Figure 2: Isoflurane Postconditioning Upregulates Phosphorylated Connexin 43 in the Middle Cerebral Artery Occlusion Model and Is Probably Associated with the TGF-<i>β</i>1/Smad2/3 Signaling Pathway 

Figure 2 | Isoflurane Postconditioning Upregulates Phosphorylated Connexin 43 in the Middle Cerebral Artery Occlusion Model and Is Probably Associated with the TGF-β1/Smad2/3 Signaling Pathway 