Isoflurane Postconditioning Upregulates Phosphorylated Connexin 43 in the Middle Cerebral Artery Occlusion Model and Is Probably Associated with the TGF-<i>β</i>1/Smad2/3 Signaling Pathway

<div>Effects of 1.5% ISPOC, TGF-<i>β</i>1 inhibitor LY2157299, p-Cx43 inhibitor Ro318220, and p-Cx43 activator 18<i>β</i>-GA on neuronal damage in the hippocampal CA1 region after cerebral ischemia/reperfusion (Nissl staining). (a) Brain sections were stained with the Nissl staining solution. The number of Nissl bodies in the hippocampal CA1 area neurons showed the extent of damage. Original magnification: 200x. Scale bars: 50 <i>μ</i>m. (b) Number of Nissl bodies in the CA1 area in each group. 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BioMed Research International

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Figure 3

Figure 3: Isoflurane Postconditioning Upregulates Phosphorylated Connexin 43 in the Middle Cerebral Artery Occlusion Model and Is Probably Associated with the TGF-<i>β</i>1/Smad2/3 Signaling Pathway 

Figure 3 | Isoflurane Postconditioning Upregulates Phosphorylated Connexin 43 in the Middle Cerebral Artery Occlusion Model and Is Probably Associated with the TGF-β1/Smad2/3 Signaling Pathway 