Review Article

Prognostic Value of N-terminal Probrain Natriuretic Peptide for Patients with Acute Respiratory Distress Syndrome: A Systematic Review and Meta-Analysis

Table 1

Characteristics of included studies.

AuthorYearCountryTested daysCut-offSurvival/nonsurvivalAUCSensitivity (%)Specificity (%)EndpointTest methodTPFPFNTN

Lin [32]2012Chinad12417 pg/mL60/270.72261.565.630 d mortalityRoche, Cobas e411 analyzer17211039
Park [26]2011Koread2Percent change 30%18/310.82828128 d mortalityRoche, Elecsys 2010 analyzer253615
Bajwa [25]2008Americad26813 ng/L107/700.66805160 d mortalityRoche, Elecsys 2010 analyzer56521455
Ji [29]2016Chinad14522 ng/L30/500.852817728 d mortalityRoche, Elecsys 2010 analyzer2411639
Zhou [30]2015Chinad1333.92 pg/mL59/280.79881.9291.8928 d mortalityNA235554
Su [27]2018Chinad1NA27/240.83279.274.128 d mortalityRoche, Elecsys 2010 analyzer197520
Xu [31]2013Chinad1335 pg/mL10/400.96080.092.528 d mortalityRoche, Elecsys 2010 analyzer83237

NA: not available; AUC: area under the curve; TP: true positive; FP: false positive; TN: true negative; FN: false negative.